2021 schedule
East Carolina
CUSA
Final rank
#4
Record
7-5
Points
17
Diff
+41
Scored
356
Allowed
315
Outcome
—
Game log
Real CFBD regular-season results. Points earned per game follow the opponent's 2021 starting tier: 5 for Tier 1, 4 for Tier 2, 3 for Tier 3, 2 for Tier 4, 1 for Tier 5, 0 for FBS losses or FCS wins, and −3 for any loss to an FCS opponent.
| Week | Opponent | Site | Score | Result | Pts |
|---|---|---|---|---|---|
| 2 | App State(Tier 4) | Away | 19 – 33 | L | 0 |
| 3 | South Carolina(Tier 3) | Home | 17 – 20 | L | 0 |
| 4 | Marshall(Tier 4) | Away | 42 – 38 | W | +2 |
| 5 | FCS opponent | Home | 31 – 28 | W | 0 |
| 6 | Tulane(Tier 3) | Home | 52 – 29 | W | +3 |
| 7 | UCF(Premier) | Away | 16 – 20 | L | 0 |
| 9 | Houston(Tier 2) | Away | 24 – 31 | L | 0 |
| 10 | South Florida(Tier 3) | Home | 29 – 14 | W | +3 |
| 11 | Temple(Tier 4) | Home | 45 – 3 | W | +2 |
| 12 | Memphis(Tier 2) | Away | 30 – 29 | W | +4 |
| 13 | Navy(Tier 3) | Away | 38 – 35 | W | +3 |
| 14 | Cincinnati(Premier) | Home | 13 – 35 | L | 0 |
