2021 schedule
Missouri
Big 12
Final rank
#16
Record
6-6
Points
13
Diff
-60
Scored
356
Allowed
416
Outcome
—
Game log
Real CFBD regular-season results. Points earned per game follow the opponent's 2021 starting tier: 5 for Tier 1, 4 for Tier 2, 3 for Tier 3, 2 for Tier 4, 1 for Tier 5, 0 for FBS losses or FCS wins, and −3 for any loss to an FCS opponent.
| Week | Opponent | Site | Score | Result | Pts |
|---|---|---|---|---|---|
| 2 | Central Michigan(Tier 4) | Home | 34 – 24 | W | +2 |
| 3 | Kentucky(Tier 3) | Away | 28 – 35 | L | 0 |
| 4 | FCS opponent | Home | 59 – 28 | W | 0 |
| 5 | Boston College(Tier 3) | Away | 34 – 41 | L | 0 |
| 6 | Tennessee(Tier 3) | Home | 24 – 62 | L | 0 |
| 7 | North Texas(Tier 4) | Home | 48 – 35 | W | +2 |
| 8 | Texas A&M(Premier) | Home | 14 – 35 | L | 0 |
| 10 | Vanderbilt(Tier 5) | Away | 37 – 28 | W | +1 |
| 11 | Georgia(Premier) | Away | 6 – 43 | L | 0 |
| 12 | South Carolina(Tier 3) | Home | 31 – 28 | W | +3 |
| 13 | Florida(Premier) | Home | 24 – 23 | W | +5 |
| 14 | Arkansas(Tier 5) | Away | 17 – 34 | L | 0 |
