2021 schedule
Notre Dame
Independent
Final rank
#1
Record
11-1
Points
40
Diff
+204
Scored
423
Allowed
219
Outcome
—
Game log
Real CFBD regular-season results. Points earned per game follow the opponent's 2021 starting tier: 5 for Tier 1, 4 for Tier 2, 3 for Tier 3, 2 for Tier 4, 1 for Tier 5, 0 for FBS losses or FCS wins, and −3 for any loss to an FCS opponent.
| Week | Opponent | Site | Score | Result | Pts |
|---|---|---|---|---|---|
| 2 | Florida State(Tier 2) | Away | 41 – 38 | W | +4 |
| 3 | Toledo(Tier 3) | Home | 32 – 29 | W | +3 |
| 4 | Purdue(Tier 4) | Home | 27 – 13 | W | +2 |
| 5 | Wisconsin(Premier) | Away | 41 – 13 | W | +5 |
| 6 | Cincinnati(Premier) | Home | 13 – 24 | L | 0 |
| 7 | Virginia Tech(Tier 2) | Away | 32 – 29 | W | +4 |
| 9 | USC(Premier) | Home | 31 – 16 | W | +5 |
| 10 | North Carolina(Tier 3) | Home | 44 – 34 | W | +3 |
| 11 | Navy(Tier 3) | Home | 34 – 6 | W | +3 |
| 12 | Virginia(Tier 3) | Away | 28 – 3 | W | +3 |
| 13 | Georgia Tech(Tier 3) | Home | 55 – 0 | W | +3 |
| 14 | Stanford(Premier) | Away | 45 – 14 | W | +5 |
