2021 schedule
Ohio State
Big Ten
Final rank
#7
Record
10-2
Points
31
Diff
+295
Scored
546
Allowed
251
Outcome
—
Game log
Real CFBD regular-season results. Points earned per game follow the opponent's 2021 starting tier: 5 for Tier 1, 4 for Tier 2, 3 for Tier 3, 2 for Tier 4, 1 for Tier 5, 0 for FBS losses or FCS wins, and −3 for any loss to an FCS opponent.
| Week | Opponent | Site | Score | Result | Pts |
|---|---|---|---|---|---|
| 2 | Minnesota(Tier 2) | Away | 45 – 31 | W | +4 |
| 3 | Oregon(Premier) | Home | 28 – 35 | L | 0 |
| 4 | Tulsa(Tier 3) | Home | 41 – 20 | W | +3 |
| 5 | Akron(Tier 5) | Home | 59 – 7 | W | +1 |
| 6 | Rutgers(Tier 5) | Away | 52 – 13 | W | +1 |
| 7 | Maryland(Tier 4) | Home | 66 – 17 | W | +2 |
| 9 | Indiana(Tier 2) | Away | 54 – 7 | W | +4 |
| 10 | Penn State(Premier) | Home | 33 – 24 | W | +5 |
| 11 | Nebraska(Tier 2) | Away | 26 – 17 | W | +4 |
| 12 | Purdue(Tier 4) | Home | 59 – 31 | W | +2 |
| 13 | Michigan State(Premier) | Home | 56 – 7 | W | +5 |
| 14 | Michigan(Tier 2) | Away | 27 – 42 | L | 0 |
