2021 schedule
Southern Miss
CUSA
Final rank
#22
Record
3-9
Points
4
Diff
-123
Scored
212
Allowed
335
Outcome
—
Game log
Real CFBD regular-season results. Points earned per game follow the opponent's 2021 starting tier: 5 for Tier 1, 4 for Tier 2, 3 for Tier 3, 2 for Tier 4, 1 for Tier 5, 0 for FBS losses or FCS wins, and −3 for any loss to an FCS opponent.
| Week | Opponent | Site | Score | Result | Pts |
|---|---|---|---|---|---|
| 2 | South Alabama(Tier 5) | Away | 7 – 31 | L | 0 |
| 3 | FCS opponent | Home | 37 – 0 | W | 0 |
| 4 | Troy(Tier 5) | Home | 9 – 21 | L | 0 |
| 5 | Alabama(Premier) | Away | 14 – 63 | L | 0 |
| 6 | Rice(Tier 5) | Away | 19 – 24 | L | 0 |
| 7 | UTEP(Tier 5) | Home | 13 – 26 | L | 0 |
| 8 | UAB(Tier 4) | Home | 0 – 34 | L | 0 |
| 10 | Middle Tennessee(Tier 4) | Away | 10 – 35 | L | 0 |
| 11 | North Texas(Tier 4) | Home | 14 – 38 | L | 0 |
| 12 | UTSA(Tier 5) | Away | 17 – 27 | L | 0 |
| 13 | Louisiana Tech(Tier 3) | Away | 35 – 19 | W | +3 |
| 14 | Florida International(Tier 5) | Home | 37 – 17 | W | +1 |
