2021 schedule
Clemson
ACC
Final rank
#12
Record
9-3
Points
23
Diff
+142
Scored
322
Allowed
180
Outcome
—
Game log
Real CFBD regular-season results. Points earned per game follow the opponent's 2021 starting tier: 5 for Tier 1, 4 for Tier 2, 3 for Tier 3, 2 for Tier 4, 1 for Tier 5, 0 for FBS losses or FCS wins, and −3 for any loss to an FCS opponent.
| Week | Opponent | Site | Score | Result | Pts |
|---|---|---|---|---|---|
| 2 | Georgia(Premier) | Home | 3 – 10 | L | 0 |
| 3 | FCS opponent | Home | 49 – 3 | W | 0 |
| 4 | Georgia Tech(Tier 3) | Home | 14 – 8 | W | +3 |
| 5 | NC State(Tier 3) | Away | 21 – 27 | L | 0 |
| 6 | Boston College(Tier 3) | Home | 19 – 13 | W | +3 |
| 8 | Syracuse(Tier 3) | Away | 17 – 14 | W | +3 |
| 9 | Pittsburgh(Tier 2) | Away | 17 – 27 | L | 0 |
| 10 | Florida State(Tier 2) | Home | 30 – 20 | W | +4 |
| 11 | Louisville(Tier 2) | Away | 30 – 24 | W | +4 |
| 12 | UConn(Tier 5) | Home | 44 – 7 | W | +1 |
| 13 | Wake Forest(Tier 4) | Home | 48 – 27 | W | +2 |
| 14 | South Carolina(Tier 3) | Away | 30 – 0 | W | +3 |
