2022 schedule
Louisville
CUSA
Final rank
#10
Record
7-5
Points
22
Diff
+84
Scored
326
Allowed
242
Outcome
—
Game log
Real CFBD regular-season results. Points earned per game follow the opponent's 2022 starting tier: 5 for Tier 1, 4 for Tier 2, 3 for Tier 3, 2 for Tier 4, 1 for Tier 5, 0 for FBS losses or FCS wins, and −3 for any loss to an FCS opponent.
| Week | Opponent | Site | Score | Result | Pts |
|---|---|---|---|---|---|
| 2 | Syracuse(Tier 3) | Away | 7 – 31 | L | 0 |
| 3 | UCF(Premier) | Away | 20 – 14 | W | +5 |
| 4 | Florida State(Tier 2) | Home | 31 – 35 | L | 0 |
| 5 | South Florida(Tier 4) | Home | 41 – 3 | W | +2 |
| 6 | Boston College(Tier 3) | Away | 33 – 34 | L | 0 |
| 7 | Virginia(Tier 3) | Away | 34 – 17 | W | +3 |
| 9 | Pittsburgh(Tier 2) | Home | 24 – 10 | W | +4 |
| 10 | Wake Forest(Tier 3) | Home | 48 – 21 | W | +3 |
| 11 | James Madison(Tier 5) | Home | 34 – 10 | W | +1 |
| 12 | Clemson(Premier) | Away | 16 – 31 | L | 0 |
| 13 | NC State(Tier 2) | Home | 25 – 10 | W | +4 |
| 14 | Kentucky(Tier 3) | Away | 13 – 26 | L | 0 |
